Copyright Policy Topically, aloe is used for skin conditions such as burns, frostbite, psoriasis and cold sores. Journal of Traditional and Complementary Medicine, National Center for Complementary and Integrative Health, National Institute of Environmental Health Sciences, Journal of Environmental Science and Health, The Benefits of Aloe Vera Juice for Weight Loss, Journal of Traditional and Complementary Medicine: "Evaluation of Biological Properties and Clinical Effectiveness of Aloe Vera: A Systematic Review", NIH: National Center for Complementary and Integrative Health: "Aloe Vera", National Institute of Environmental Health Sciences: National Toxicology Program: "Aloe Vera", Journal of Environmental Science and Health: "Aloe vera: A Review of Toxicity and Adverse Clinical Effects", StatPearls [Internet]: Treasure Island (FL): "Melanosis Coli", Mayo Clinic: "Over-the-Counter Laxatives for Constipation: Use With Caution", U.S. Library of Medicine: "Digitalis Toxicity", Indian Journal of Dermatology: "Drug Interactions in Dermatology: What the Dermatologist Should Know", PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. However, taking aloe vera by mouth is known to have significant stimulant laxative effects, which could potentially alter how oral drugs taken at … Now retired, Gord enjoys a quiet life on a small island in the Gulf Islands of B.C. Due to its potential healing attributes, the pulp of the aloe has traditionally been used to make a clear gel for topical use, or a yellow latex oral form, as a remedy for a wide range of clinical uses. Aloe contains proteins, lipids, amino acids, vitamins, inorganic and small organic compounds, enzymes and various carbohydrates. LIVESTRONG.com may earn compensation through affiliate links in this story. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Privacy Policy Copyright © 0 … 3. and Clinical trial in diabetes mellitus patients in combination with glibenclamide. Low potassium might increase the side effects of digoxin. Since 2014, she has contributed to over 15 digital publications. Always talk to your doctor before mixing aloe vera with any medications. While small amounts of aloe vera juice can help combat constipation and improve digestion, pure aloe vera juice in large quantities can cause diarrhea, stomach cramps, dehydration, and electrolyte imbalances. Dangerously low levels of potassium can lead to fatigue, muscle weakness, irregular heartbeats and even hypokalemia. Drug Interactions. Aloe Vera Side Effects, Drug Interactions and Contraindications Caution should be taken when ingesting aloe vera as there can be potential side effects. In some cases, aloe can reduce the bioavailability or block the action of the co-administered drug. Aloe vera juice can decrease blood sugar, and this could cause a problem with diabetes medications (1). Read more: The Benefits of Aloe Vera Juice for Weight Loss. View abstract. About Aloe Juice. For this reason, if you are taking medication, I highly recommend that you consult your doctor before taking juices, or other products based on Aloe Vera, or Arborescens. Additionally, the long-term use of aloe vera juice as a laxative may interfere with the absorption of medications and nutrients, according to the January 2020 publication of Melanosis Coli. Does DH Aloe Vera have any drug interactions? Read more: Aloe Vera Juice Storage Information. This side effect can occur due to couple of reasons like the quality of the aloe vera juice, over dosage of juice, extra additives present in the juice, etc. Make sure you only drink aloe vera juice that has been decolorized (purified) to reduce aloin levels. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Aloe Vera also appears to enhance the absorption of some vitamins. Highly clinically significant. The juice exerts anti-platelet effects and may interfere with drugs like warfarin (used as a blood thinner) (53). Contraindications. Phytomedicine 1996;3:245-8. Gordon Kerr has worked in the health care industry for the past 15 years. Aloe gel should not be confused with aloe juice or aloe latex, both of which contain anthraquinone, a potent laxative. Drug Interactions risk of hypoglycemia (additive effects) diagnosis or treatment. Juice containing aloe vera may add variety to your beverage intake, but be aware that many of its beneficial health claims are unsubstantiated. Avoid combinations; the risk of the interaction outweighs the benefit. [Letter. We would like to show you a description here but the site won’t allow us. If you are taking any drug that is considered a substrate of … Minimally clinically significant. , Cascara sagrada, aloe laxatives, O-9 contraceptives are category II-FDA. An electrolyte imbalance can cause weakness, confusion, abnormal heart rhythms and seizures. An evergreen perennial, it originates from the Arabian Peninsula, but grows wild in tropical, semi-tropical, and arid climates around the world. Don't take aloe latex and digoxin together. This medication contains aloe. Avoid aloe vera if you have an allergy to any plants in the Liliaceae family. You might also like: What are the Benefits of aloe vera gel for natural hair. Consuming it in conjunction with diabetes medications can cause hypoglycemia. Speak with your doctor if you intend to drink aloe vera juice and take any of the following drugs or supplements, in addition to the ones already mentioned: In addition to the risk of aloe vera interactions with medications, the use of aloe vera preparations should be avoided if you have an allergy to plants of the Liliaceae family (garlic, onions, and tulips). It should not be out on mice showed that Aloe vera taken orally is likely to trigger colon cancer;[48] and another study showed that Aloe vera may increase skin cancer induced by ul-traviolet rays. Aloe vera extract 0.5% in a hydrophilic cream versus Aloe vera gel for the management of genital herpes in males. Common interactions include irritable bowel syndrome among females and dizziness among males. However, a review published in the Journal of Environmental Science and Health in January 2019 reported that aloe vera whole leaf extract showed evidence of carcinogenic activity in animals and was classified as a possible human carcinogen. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse Digoxin (Lanoxin). Side effects of aloe vera juice range from mild to severe like diarrhea or skin irritation. Quinidine Cardiac glycosides 2,3,5,11,12 e.g. Drug interactions and 21 reactions for Aloe Vera (Gel, Juice, Leaf). Digoxin 5 Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. So, monitor your dose of aloe vera and consider healthcare professional in case you notice this side effect of aloe vera. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Proponents claim that aloe vera can even speed the healing of wounds and reduce the severity of psoriasis. Aloe vera juice can have some unhealthy outcomes when mixed with some medicines. Moderate interactions with aloe. When taken orally as a juice or dietary supplement, aloe vera's laxative effects can help ease constipation. According to the National Institute of Environmental Health Sciences, the outer leaf pulp of aloe leaves used to make juice is made up of an organic component known as latex, which contains anthraquinones. According to The MSKCC (Memorial Sloan-Kettering Cancer Center), Aloe Vera can constrain the effects of this enzyme and this can result in increased concentrations of the medicine in the body, thus resulting in a danger of experiencing serious side effects. risk of hypoglycemia (additive effects) : combo may incr. Show all medications in the database that may interact with aloe vera. A laboratory study showed that the plant juice of Aloe vera inhibits the 2. These types of drugs, herbs and supplements reduce blood clotting. Many drugs can be affected by combining them with supplements including aloe vera capsules and drinks made from the leaves of the plant. 3. Although a popular health drink, be aware that aloe vera interactions with medications may cause adverse consequences and alter the effectivenes of some drugs. Aloe vera, when taken orally, can interact with oral diabetes medications and cause hypoglycemia (low blood sugar). The study is created by eHealthMe based on reports of 84 people who take Aloe vera and Omeprazole from the FDA, and is updated regularly. Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L juice. Herb Drug Class Type of Interaction 3 Alfalfa (Medicago sativa)-Leaf Aloe Vera - (A. vera) Latex Powder Aloe Vera-Gel or Juice Anticoagulants 2,4,9 e.g. Although generally considered safe when used topically, aloe vera capsules or juice taken orally can react with certain drugs. Terms of Use aloe vera. Warfarin 3 Hormone replacement therapy 2,4,9 Oral contraceptives 2,4,9 Xenobiotics 3 All drugs 12 Antiarrythmic agents 5,11,12 e.g. A total of 45 drugs are known to interact with Aloe can interact with some drugs, enhancing or reducing their effects. Oral use of aloe might also slow blood clotting. Aloe juice comes from the green part of the aloe leaf located just below the skin and it surrounds the gel. risk of hypokalemia, QT prolongation, cardiac arrhythmias (additive effects) Aloe Vera Drug Interactions. Consider the following interactions: Major interactions with aloe: Aloe latex when taken by mouth becomes a stimulant laxative that can decrease potassium levels in the body. The 2015 study.Drug interactions — Aloe vera juice may interact negatively with certain drugs or medications, either inhibiting or enhancing the effects. View interaction reports for aloe vera and the medicines listed below. Drug interactions — Aloe vera juice may interact negatively with certain drugs or medications, either inhibiting or enhancing the effects. As a dietary supplement or juice, aloe vera may be used for osteoarthritis, bowel diseases, fever and constipation, according to National Center for Complementary and Integrative Health (NIH). Her work has appeared on nutrition and health websites such as SparkPeople, CureJoy, and Healthline. None reported Anthraquinones, such as aloin, give the plant its laxative qualities. any of the products or services that are advertised on the web site. Aloe vera juice is a potent laxative and is often used to cleanse the digestive system or relieve constipation. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Aloe vera gel is often applied to the skin to treat sunburn, burns, and eczema. When taken orally for prolonged periods with diuretics or digoxin, it can lead to low blood levels of potassium (hypokalemia) due to diarrhea. Aloe vera is a succulent plant — one of more than 400 species of the genus Aloe — originating in South Africa and belonging to the Liliaceae family, according to an article in the Journal of Traditional and Complementary Medicine published in December 2014. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Aloe vera interactions with medications can reduce bioavailability, making drugs less effective, or increase the response that may trigger negative reactions and side effects. Aloe vera review. The Mayo Clinic warns that many oral laxatives may also lead to dehydration and the risk of an electrolyte imbalance, especially after prolonged use. For this reason, aloe vera juice and antibiotics are not a good combination, nor are some heart and bone medications, says the Mayo Clinic. Select one or more newsletters to continue. aloe + chlorpropamide monitor glucose: combo may incr. Taking aloe orally with either of these types of medications might lead to increased bleeding. The species is also used for decorative purposes and grows successfully indoors as a potted plant. 2020 As well as educating the under-nourished people in the region, Gordon formulated dietary plans to help manage medical conditions including chronic nutrition-related diseases, such as diabetes and hypertension. Anticoagulants and anti-platelet drugs, herbs and supplements. If consumed in excess, aloe vera juice can cause cramping, dehydration, and pain as well. Do not take Aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, or Aloe vulgari if you are allergic to aloe or any ingredients contained in this drug. The laxative property of aloe vera inhibits absorption of several drugs in the body. ... Drug Interactions. A placebo-controlled, double-blind, comparative study. Medscape - Indication-specific dosing for aloe vera, Aloe arborescens natalenis, Aloe barbadensis, Aloe ferox, Aloe vulgari (aloe), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Keep out of reach of children. Drug interactions . Aloe vera (also known as Aloe barbadensis Mill., Aloe indica Royle, Aloe perfoliata L. var. Electrolytes including calcium, chloride, potassium, magnesium and sodium regulate many body functions. Low potassium levels increase the risk of side effects of digoxin (Lanoxin). Find everything you need to know about Aloe Vera Topical (Coats Aloe), including what it is used for, warnings, reviews, side effects, and interactions. used as a substitute for professional medical advice, The reduced transit time accelerates the gastrointestinal emptying, which means decreased bioavailability of medications and quick secretion with your feces. Use of this web site constitutes acceptance of the LIVESTRONG.COM Oral use of aloe latex can decrease potassium levels. I haven't seen anyone say so but I just wanted to make sure. Always talk to your doctor before mixing aloe vera … With his passion for a healthy lifestyle and the desire to help others benefit from proper nutrition and natural remedies, Gordon accepted the international position with CARICOM Regional Food and Nutrition in the Caribbean and moved to Barbados. I know Marshmallow Root needs to be taken an hour or two before or after other medications because it inhibits the absorbtion of other drugs but does this apply to Aloe Vera as well? The aloe latex—the yellow juice near the rind—is where most of the danger lies. He holds a diploma in Food and Nutritional Science from CSNN, Canadian School of Natural Nutrition, Vancouver. turmeric, echinacea, milk thistle, creatine, saw palmetto. Reports from the publication suggest that anthraquinones in aloe vera inhibit the reabsorption of water, sodium, potassium and any oral medication you may be taking in. Aloe vera juice can also interact with sevoflurane (used as anesthesia during surgery) (52). Possible interactions include: 1. In addition, an article in the Indian Journal of Dermatology published in July-August 2013 warns that combining aloe vera with prednisolone, used as an anti-inflammatory and immunosuppressant, can induce a loss of potassium in the body. Here are some drugs with which Aloe can have interactions: anti-arrhythmic drugs; To avoid serious potassium loss, do not drink aloe vera juice with diuretics such as thiazide, or heart medications such as digitalis, both of which are used to help remove excess fluid and lower potassium levels. The Tan Sheet May 13, 2002. If you have diabetes, you may want to ask your health care provider first before trying out Aloe for the first time. ... Aloe vera is usually considered a wonder drug to treat cuts and burns, but for some people it can be just the opposite. We comply with the HONcode standard for trustworthy health information -, Fish Oil (omega-3 polyunsaturated fatty acids), Glucosamine & Chondroitin with MSM (chondroitin / glucosamine / methylsulfonylmethane), Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus). Kirsten Nunez, MS is a health and lifestyle journalist based in Beacon, New York. Use caution when using aloe vera together with the following medications: Antidiabetes medications: Aloe gel may decrease blood sugar levels. Usually avoid combinations; use it only under special circumstances. Reports of drug interactions with aloe vera latex include a list of drugs such as diuretics, steroids, and digoxin. . 13. The human body comprises of various enzymes which metabolize substances, like drugs or herbs which come via your body. Some mixtures of medications can lead to serious and even fatal consequences. advertisements are served by third party advertising companies. Learn the usage methods to enjoy its benefits without any problems. Type in a drug name to check for interactions with aloe vera. In others, it can enhance the effect of the medication, triggering or worsening side effects of the drug. Diarrhea is another side effect of consuming aloe vera juice. Despite the use of some oral dosages in clinical trials of ulcerative colitis, there is not enough evidence at this time to support the use of aloe vera by mouth or by injection. Not only is aloe vera juice made from latex or whole-leaf extract likely to be unsafe in high doses, but also excessive intake for several days can cause acute kidney failure and can be fatal, according to the Mayo Clinic. Although a popular health drink, be aware that aloe vera interactions with medications may cause adverse consequences and alter the effectivenes of some drugs. Aloe vera (/ ˈ æ l oʊ iː / or / ˈ æ l oʊ /) is a succulent plant species of the genus Aloe. II. Also, aloe latex has been shown to influence the effectiveness of blood pressure medications, potassium-sparing drugs, and medications used in diabetes. In regard to drug interactions with oral aloe products, there isn't much data to indicate any major interactions. When taking Aloe Vera internally, you must know that it can interact with certain prescription medications. Drug Interactions With Aloe Vera. Moderately clinically significant. ALOE VERA / KUMARI (Aloe vera babadensis): Aloe Vera may have blood-glucose-lowering properties and may therefore be expected to interact with conventional drugs that have the same effect. It is also beli… ]. Many biological antibacterial and antimicrobial properties are associated with the pulp of the aloe leaves. It is cultivated for agricultural and medicinal uses. Available for Android and iOS devices. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. Aloe vera juice is generally considered safe but can cause unhealthy outcomes if combined with some medications or other supplements. Drug interactions are reported among people who take Aloe vera and Omeprazole. In case of overdose, get medical help or contact a Poison Control Center immediately. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Common interactions include pulmonary oedema among females and dizziness among males. Many people experience aloe vera side effects from using it as a laxative, which can include diarrhea and abdominal cramps. Leaf Group Ltd. Kirsten has a Master of Science in Nutrition and Bachelor of Science in Dietetics. aloe + arsenic trioxide use alternative or monitor potassium w/ aloe laxative doses: combo may incr. Drug interactions with aloe vera juice Aloe juice has been shown to interact with certain medications. It has a soothing effect that may aid in the treatment of genital herpes, poison oak, poison ivy, and radiation-induced skin reactions. It may also decrease the efficacy of several diabetes medications and cause the potassium levels to deteriorate if consumed with water pills or diuretics. Aloe juice is … Certain studies suggest that aloe may decrease blood sugar. Aloe contains two types of substances in its leaf, including a clear gel and a yellowish liquid called aloe juice or latex. Many drugs you take orally can become less effective when combined with aloe vera juice. [49] In the literature, there is also evidence regarding drug interactions with Aloe vera. The study is created by eHealthMe based on reports of 30 people who take Aloe vera and Metformin from the FDA, and is updated regularly. Drug interactions are reported among people who take Aloe vera and Metformin. The material appearing on LIVESTRONG.COM is for educational use only.

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